Physiochemical, Mechanical and Antibacterial Properties of Sodium Alginate/Copper Oxide BioComposite Film for Wound Healing Applications

Abstract

The objectives of this study are to fabricate alginate and copper
oxide biocomposite film via solution casting method. At the earlier stage,
the alginate solution with 1wt% was prepared and later mix with the 0.5, 1.0
and 1.5 gram of copper oxide. The combination of alginate and copper oxide
was stirred for 3 minutes before proceeding to casting process and left for 24
hours. When the films are ready, it was crosslinked with calcium chloride.
The biocomposite film was dried in the room temperature for 24 hours. Then,
the fabricated film was characterised and analysed by using Fourier
Transform Infrared Spectroscopy (FTIR) and contact measurement, thickness
analysis and viscosity analysis also being conducted in order to study the
characterization of the film. Also the antibacterial assessment was carried out
by using disc diffusion method (Kirby-Bauer test).