Study on Morphological Properties of Polyvinyl Alcohol/Poly(lactic acid) Wound Dressing Membrane as Drug Delivery Carrier in Wound Healing Treatment

  • Celine Ng
  • Mohd Syahir Anwar Hamzah
  • Saiful Izwan Abd Razak
  • Jumadi Abdul Sukor
  • Nafarizal Nayan
  • Nadirul Hasraf Mat Nayan UNIVERSITI TUN HUSSEIN ONN
Keywords: Wound, electrospinning, polyvinyl alcohol, poly (lactic acid), morphological

Abstract

Wound dressing have experienced continuous improvement and changes since ancient time. Electrospinning of polymeric nanofibers have captured the interest of researchers due to its simplicity and cost effective technique that able to produce wound dressing membrane that meet the requirement as ideal wound dressing and drug delivery carrier. In this work, polyvinyl alcohol (PVA) and poly (lactic acid) (PLA) were chosen polymer to produce wound dressing membrane through electrospinning and coating method. PVA was electrospun and then coated with PLA. The aim of this study was to investigate the morphological properties of PVA/PLA wound dressing membrane. Based on the results from Atomic Force Microscope, PVA nanofiber coated with 4% PLA exhibit the highest value of Rq which is 0.47 ± 0.19 μm compared to neat PVA nanofibers membrane. Field Emission Scanning Electron Microscope (FE-SEM) image revealed that PVA nanofiber coated with 4% PLA shows porous fiber-like morphology and well incorporated with each other without any gap formed between them. This report clearly suggestive of the fact that synthetic biodegradable polymers such as PLA can be exploited for the synergistic combination with PVA nanofiber for wound dressing application.

Author Biography

Nadirul Hasraf Mat Nayan, UNIVERSITI TUN HUSSEIN ONN
CHEMICAL ENGINEERING TECHNOLOGY DEPARTMENT
Published
11-12-2020
How to Cite
Ng, C., Hamzah, M. S. A., Abd Razak, S. I., Abdul Sukor, J., Nayan, N., & Mat Nayan, N. H. (2020). Study on Morphological Properties of Polyvinyl Alcohol/Poly(lactic acid) Wound Dressing Membrane as Drug Delivery Carrier in Wound Healing Treatment. Journal of Advanced Industrial Technology and Application, 1(2), 7-11. Retrieved from https://publisher.uthm.edu.my/ojs/index.php/jaita/article/view/6606
Section
Articles

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